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Customized fill release for soft caps

机译:Customized fill release for soft caps

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Celatin capsules are among the most popular dosage forms for pharmaceutical applications, over-the-counter (OTC) products and dietary supplements. And with good reason: Thanks to their smooth surface, they are easy to swallow and thus facilitate regular intake of certain active ingredients and nutrients. Also, gelatin is non-allergenic and consists of proteins that are easily digested in the gastrointestinal tract. However, when a delayed release is desired - which is critical for some substances - or capsules are exposed to difficult storage conditions, there is a limit to what the conventional pharmaceutical gelatin can achieve. That's why CELITA has developed some very specific variants that give capsule manufacturers full control over the release of active ingredients. Although there are many different kinds of substances provided in capsules, not every capsule type is suitable for every kind of fill. For example, for liquids or pasty substances soft gels are usually the first choice, while granules or powders are mostly delivered in hard capsules. Compared to solid fillings, liquids have the advantage of being easier to digest. This can improve the bioavail- ability of ingredients or even the absorption of poorly soluble drugs.

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    《Innovations in food technology》 |2022年第94期|31-33|共3页
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  • 正文语种 英语
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