首页> 外文期刊>American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons >Predictors of survival following liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma: Experience from the Society of Pediatric Liver Transplantation (SPLIT)
【24h】

Predictors of survival following liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma: Experience from the Society of Pediatric Liver Transplantation (SPLIT)

机译:Predictors of survival following liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma: Experience from the Society of Pediatric Liver Transplantation (SPLIT)

获取原文
获取原文并翻译 | 示例
           

摘要

Management of unresectable pediatric hepatoblastoma (HB) and hepatocellular carcinoma (HCC) remains challenging. The Society of Pediatric Liver Transplantation (SPLIT) database was used to study survival predictors in pediatric liver transplantation (LT) for HB and HCC. Event‐free survival (EFS), associated risk factors, and postoperative complications were studied in children requiring LT for HB/HCC at 16 SPLIT centers. Three‐year EFS was 81 for HB (n?=?157) and 62 for HCC (n?=?18) transplants. Of HB transplants, 6.9 were PRETEXT II and 15.3 were POST‐TEXT I/II. Tumor extent did not impact survival (p?=?NS). Salvage (n?=?13) and primary HB transplants had similar 3‐year EFS (62 versus 78, p?=?NS). Among HCC transplants, 3‐year EFS was poorer in older patients (38 in ≥8‐year‐olds vs 86 <8‐year‐olds) and those with larger tumors (48 for those beyond versus 83 within Milan criteria, p?=?NS). Risk of infection (HR 1.5, 95 CI 1.1–2.2, p?=?.02) and renal injury (HR 2.4, 95 CI 1.7–3.3, p?

著录项

获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号