CO 2 laser-assisted sclerectomy surgery in the treatment of open-angle glaucoma in Chinese patients

摘要

Purpose: To evaluate the efficacy and safety of CO_(2)-Laser Assisted Sclerectomy Surgery (CLASS) with 5-fluorouracil (5-FU) in treating open-angle glaucoma (OAG) in Chinese patients. Methods: This was a retrospective, uncontrolled, interventional case series. All patients from 2016 to 2017 who received CLASS were recruited in this study. The primary outcome was the change in intraocular pressure (IOP) and the number of IOP-lowering medications over a 12-month follow-up period. Adverse events were evaluated as secondary outcomes. Results: Data were collected from forty-two eyes of 31 patients. The average preoperative IOP was 31.33?±?7.60mmHg. The mean percentage of IOP reduction from baseline at postoperative months (POM) 1, 3, 6, 9, and, 12 were 48.1?±?24.6, 51.4?±?19.3, 51.2?±?17.2, 50.9?±?15.0, 49.2?±?16.3, respectively (all P ?