Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position

摘要

A protocol for visible-light-induced C–H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This protocol allows the green, mild, and efficient functionalization of various purine nucleosides with a broad range of alkyl and aryl aldehydes.