Surgical treatment of spinal deformities in spinal muscular atrophy: a single-center experience from China

摘要

Abstract Purpose To report the clinical characteristics and surgical outcomes of scoliosis in patients with spinal muscular atrophy (SMA) from Mainland China.Methods Nineteen patients were retrospectively analyzed. Demographic, anthropometric and respiratory parameters were collected preoperatively. Surgical program was analyzed. Radiographic data were measured perioperatively. Motor status, ventilation support, sitting ability and respiratory symptoms were evaluated preoperatively and at final follow-up.Results Age at surgery was 17.08 (12.83, 20.08) years. More than 40 of patients were diagnosed with low weight. Pulmonary dysfunction was observed in all patients. All patients received posterior spinal fusion (PSF). Sacroiliac fixation with sacral-2 alar iliac technique was used in 16 patients. Major curve correction rate was 54.87?±?16.14. Pelvic obliquity correction rate was 63.84?±?23.70. T1–T12 height, space-available-for-lung ratio and thoracic transverse diameter were increased (p?