Body mass index trajectories in early childhood in relation to cardiometabolic risk profile and body composition at 5 years of age

摘要

Background: Both impaired and accelerated postnatal growth have been associated with adult risks of obesity and cardiometabolic diseases, like type 2 diabetes and cardiovascular disease. However, the timing of the onset of cardiometabolic changes and the specific growth trajectories linking early growth with later disease risks are not well understood.