Population Structure of Macaca fascicularis aurea, and their Genetic Relationships with M. f. fascicularis and M. mulatta Determined by 868 RADseq‐Derived Autosomal SNPs—A consideration for biomedical research

摘要

Abstract Background This study examined the population structure of Macaca fascicularis aurea and their genetic relationships with M. f. fascicularis and M. mulatta. Methods The study analyzed 868 RADseq‐derived SNPs from samples representing the entire distribution range of M. f. aurea, including their inter‐ and intraspecific hybrid zones. Results The study supports a M. mulatta/Indochinese M. f. fascicularis, Sundaic M. f. fascicularis, and M. f. aurea trichotomy; M. f. aurea was genetically distinct from both forms of M. f. fascicularis and M. mulatta. Hybridization between M. f. aurea and M. f. fascicularis occurred in two directions: south‐north (8°25′ to 15°56′) and west‐east (98°28′ to 99°02′). Low levels of M. mulatta introgression were also detected in M. f. aurea. Conclusion This study showcases a complicated scenario of genetic relationships between the M. fascicularis subspecies and between M. fascicularis and M. mulatta and underscores the importance of these taxa's population structure and genetic relationships for biomedical research.