Fabrication of a Composite Monolithic Column of Poly (IL@MOF) for Adsorption of Acacetin in Medicinal and Food Homologous Plants

摘要

In this study, a poly (IL@MOF) composite monolithic column was synthesized using a simple and easy method. By adjusting the ratio of monomers, porogenic agents and cross-linking agents, a macroporous composite monolith composed of metal organic framework (MOF) and ionic liquids (IL) was constructed. It was used as a high-performance solid phase extraction (SPE) sorbent for the extraction of acacetin from medicinal and food homologous plants. The proposed SPE-HPLC method for determination of acacetin had the advantages of high precision (0.06 similar to 1.00 ), wide linear range (0.01 similar to 250 mu g mL(-1)) and low detection limits (3.26 ng mL(-1)). The poly (IL@MOF) monolithic column had excellent repeatability as an adsorbent. After 300 adsorption/desorption cycles, the corresponding chromatographic signal had no obvious change. These results indicated that the poly (IL@MOF) composite monolithic column was an ideal adsorbents and that the proposed method had potential for the enrichment and purification of flavonoids from medicinal and food homologous plants.