Clinical study to evaluate the efficacy of a compound Unani herbal formulation Sharbat-e Unsul Murakkab in Sual-e-Muzmin (chronic bronchitis)

摘要

The present clinical study was undertaken as a single blindplacebo controlled study to determine the efficacy of the test drug in the treatment of chronic bronchitis as there is no curative treatmentavailable for chronic bronchitis in modern medicine. Unani compoundformulation i.e. Sharbat-e-Unsul Murakkab and placebo were given in the two groups of 20 diagnosed patients in each, of chronic bronchitis during winter cough in Unani OPD Majeedia Hospital, New Delhi. Theclinical, hematological and biochemical changes were observedand recorded accordingly. The response in patients of acute exacerbation ofchronic bronchitis, using a patient directed diary card incorporating sputum characteristics and symptoms were assessed. The study revealed that the test drug is safe and significantly reduced thesigns and symptoms of chronic bronchitis in comparison to placebo i.e. cough, sleep disturbance, sputum purulence, volume, viscosity, Rhonchi, Dyspnoea, and PEFT.