Welcome to the fourth in Animine's series of articles, which reviews scientific literature on the effects of the pharmacological dosage of zinc oxide (ZnO) in weaned piglet diets. In the European Union, medicated ZnO has been totally banned since June 2022. It is interesting to note that abroad there is also a growing number of countries following this trend, such as China, where the supplementation of pharmacological levels of ZnO is already restricted. The pharmacological dosage of ZnO is well known for its effect on diarrhoea reduction and improved weight gain of weaned piglets. However, even after decades of use, there is still no consensus on its modes of action. This series of articles reviews existing scientific literature with a particular focus on its key effects and mechanisms. It will also be inspired from the latest outcomes of the zincOsupp research network supervised by Animine. This ambitious scientific programme, involving several renowned universities, addresses the suppression of pharmacological ZnO, while studying the proper supplementation of the potentiated zinc source, HiZox.
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