Copper (I) bromide (CuBr): a highly efficient catalyst for the synthesis of beta-enaminone derivatives using ultrasound irradiation under solvent-free conditions

摘要

The development of novel, clean, and efficient methods for the preparation of compounds is a major research focus in organic chemistry at the moment. In this context, copper bromide (CuBr) has been utilized as a heterogeneous catalyst for a highly efficient, eco-sustainable, and greener synthesis of beta-enaminone derivatives by condensation of 1,3-diketones with various primary amines at room temperature under ultrasound irradiation and solvent-free conditions. The structure of the synthesized compounds was confirmed by H-1, C-13 NMR spectroscopy, IR spectroscopy, and elemental analysis. The desired products were obtained in excellent yields (90-98%) within short reaction times (20-50 min).