Low rates of neurological abnormalities in patients with pigmentary mosaicism: A retrospective cohort study from a tertiary dermatology center

摘要

Background: Pigmentary mosaicism (PM) is a descriptive term encompassing a range of hyper-and hypo-pigmented phenotypes in various patterns. Information from the neurology literature initially noted neurological abnormalities (NA) in up to 90% of children with PM. The dermatology literature suggests lower associated rates (15%-30%) of NA. Variations in terminology, inclusion criteria, and small population sizes makes interpreting existing PM literature complicated. We aimed to assess rates of NA in children presenting to dermatology with PM.Methods: We included patients = 4 body sites affected were more likely to have NA (p = 4 body sites involved were associated with higher rates of NA.