Complement‐independence of tolerance induction

摘要

AbstractIn vivodepletion of plasma complement by the purified C3‐cleaving protein of cobra venom (CoF) had no effect on the induction of tolerance in adult mice to either thymus‐dependent or thymus‐independent antigens. This contrasts with the suppressive effect of CoF on, and the requirement for C3 in, the induction of thymus‐dependent antibody productionin vivoandi