Pd(ll) catalyzed regioselective ortho arylation of 2-arylpyridines, 1-phenyl-1H-pyrazoles, and N-pyridinylcarbazoles with diaryliodonium salts

摘要

This paper describes a one-pot, concise protocol for highly regioselective ortho-selective mono arylation of 9-(pyridin-2-yl)-9H-carbazoles, 2-phenylpyridines, and 1-phenylpyrazoles employing Pd(II) catalysis, employing diphenyliodonium chloride as aryl source via C-H bond activation. This C-C bond formation methodology is applicable for wide array of heterocyclic scaffolds to deliver desired arylated products in good yields.