Tirbanibulin (Klisyri) for the Treatment of Actinic Keratosis

摘要

Adverse effects associated with tirbanibulin include vesiculation/pustulation (mild: 7, moderate: less than 1, severe: less than 1) and erosion/ulceration (mild: 9, moderate: 3, severe: 0) localized to the treated area of skin. These symptoms have been shown to resolve with discontinuation of therapy.1 There are no data on the use of tirbanibulin in pregnant patients or its effects on breastfed infants, milk production, or levels of tirbanibulin in breast milk.1 Animal studies indicate there are no adverse effects on offspring.