EXPERIMENTAL STUDY ON EFFECTS OF NIGELLA SATIVA SEEDS ON SOME BLOOD COMPONENTS AND COAGULATION IN MALE GOATS

摘要

This study was done to investigate effects of Nigella sativa seeds on some blood components and coagulation. Selected number of clinically healthy male goats (Capra hicus) aged 1-2 years, weighing 26 - 34 kg were divided into 4 groups: 1) control group untreated animals, 2), 3), 4) groups- were given black seeds suspension daily for 10 days orally as the following doses respectively 100 mg / kg, 250 mg / kg, 1 g / kg of body weight. Blood samples were taken from jugular vein to determine the studiedparameters. The results revealed that Nigella sativa seeds aqueous suspension didn't change the values of Hb, total RBCs counts, total WBCs counts, neutrophils per cent (N%) lymphocytes per cent (L%) and neutrophil / lymphocytes ratio (N/L) in differentgroups. It was noticed that the use of 1 g / kg didn't relieve any bad effects but it maintained the parameters at physiological value although 1 g = 10 times the first dose and don't let any toxic effects. On the other hand, it was noticed significantlythe clear effects of the seeds with regard to increased blood platelets count which complained with decreased in coagulation time as dose dependent manner in a positive relation with passage of days.