Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity

Yoshikazu Hiraga; Mariko Ago; Munetaka Tokumasu; Ken Kaku; Katsuo Ohkata

首页> 外文期刊>Australian Journal of Chemistry: A Journal for the Publication of Original Research in All Branches of Chemistry >Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity

【24h】

Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity

机译：旨在研究其生物活性的结构-活性关系的设计的皂苷酸A类似物的合成。

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Analogues of hippospongic acid A, which inhibit the gastrulation of sea urchin embryos, were synthesized. From a study on structure-activity relationships, the conjugated carboxylic acid moiety was found to be an essential feature for biological activity.

机译：合成了抑制海胆胚胎胃化的马六甲酸A的类似物。通过对结构-活性关系的研究，发现共轭羧酸部分是生物活性的基本特征。

著录项

来源
《Australian Journal of Chemistry: A Journal for the Publication of Original Research in All Branches of Chemistry》 |2000年第12期|共4页
作者
Yoshikazu Hiraga; Mariko Ago; Munetaka Tokumasu; Ken Kaku; Katsuo Ohkata;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
gastrulation; hippospongic acid A; structure-activity relationship; synthesis;

机译：胃排泄;脂联酸A;构效关系;合成;

相似文献

外文文献
中文文献
专利

1. Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity [J] . Yoshikazu Hiraga, Mariko Ago, Munetaka Tokumasu, Australian Journal of Chemistry: A Journal for the Publication of Original Research in All Branches of Chemistry . 2000,第11a12期

机译：旨在研究其生物活性的结构-活性关系的设计的皂苷酸A类似物的合成。
2. Discovery of Aporphine Analogues as Potential Antiplatelet and Antioxidant Agents: Design, Synthesis, Structure-Activity Relationships, Biological Evaluations, and insilico Molecular Docking Studies [J] . Sharma Vashundhra, Jaiswal Pradeep K., Kumar Surendra, ChemMedChem . 2018,第17期

机译：发现白血孔类似物作为潜在的抗血小板和抗氧化剂：设计，合成，结构 - 活动关系，生物学评估和Insilico分子对接研究
3. Synthesis, biological evaluation, and structure-activity relationships of 2-[2-(benzoylamino)benzoylamino]benzoic acid analogues as inhibitors of adenovirus replication [J] . ?berg C.T., Strand M., Andersson E.K., Journal of Medicinal Chemistry . 2012,第7期

机译：2- [2-（苯甲酰氨基）苯甲酰氨基]苯甲酸类似物作为腺病毒复制抑制剂的合成，生物学评价和构效关系
4. Synthesis, Structure-Activity Relationship and Antioxidant Activity of Uric Acid Analogues. [C] . K. Takahashi, T. Kakinoki, D. Yasuda, Europe Meeting of the Society for Free Radical Research . 2009

机译：尿酸类似物的合成，结构 - 活性关系和抗氧化活性。
5. Synthesis of new glutamate receptor probes: I. Total synthesis of dysiherbaine, a potent glutamate receptor excitotoxin; II. Design and synthesis of dysiherbaine analogues; III. Synthesis and structure-activity relationships of substituted benzothiadiazides and their role as AMPA receptor modulators. [D] . Phillips, Dean Paul. 2001

机译：新型谷氨酸受体探针的合成：I. dysiherbaine的全合成，一种有效的谷氨酸受体兴奋性毒素；二。 dysiherbaine类似物的设计和合成；三，取代的苯并噻二叠氮化物的合成及其构效关系及其作为AMPA受体调节剂的作用。
6. An Entirely SPPS-Based Strategy for Synthesis of GBAP Analogue Libraries: Investigating the Structure-Activity Relationships of the Enterococcus faecalis Quorum Sensing Signal [O] . Dominic N. McBrayer, Brooke K. Gantman, Crissey D. Cameron, -1

机译：一种完全基于SPPS的GBAP模拟文库合成策略：研究粪肠球菌群体感应信号的结构-活性关系。
7. Pyridonecarboxylic Acids as Antibacterial Agents. IX. Synthesis and Structure-Activity Relationship of 3-Substituted 10-(1-Aminocyclopropyl)-9-fluoro-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acids and Their 1-Thio and 1-Aza Analogues. [O] . Yozo TODO, Hiroyasu TAKAGI, Fumihiko IINO, 1994

机译：吡啶羧酸作为抗菌剂。 IX。 3取代的10-（1-氨基环丙基）-9-氟-7-氧代-2,3-二氢-7H-吡啶（1,2,3-DE）-1,4-苯并恶嗪的合成和结构 - 活性关系-6-羧酸及其1-Thio和1-AZA类似物。
8. Photosensitive Probes into the Tubulin Binding Domain of Cryptophycins: Synthesis and Structure-Activity Relationship of C16 Aromatic Side Chain Analogues [R] . Eggen, M. 1999

机译：光敏探针进入Cryptophycins的微管蛋白结合域：C16芳香侧链类似物的合成和结构 - 活性关系

Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity

摘要

著录项

相似文献

相关主题

期刊订阅