Background: Fluoropyrimi-dines 5-fluorouracil (5-FU) and capecitabine are antimetabolite drugs used for the treat-ment of colorectal, breast, head, and neck malignancies. Different clinical manifesta-tions of fluoropyrimidine-induced cardio-toxicity (FIC) have been reported in the lit-erature. Case report: A 46-year-old female patient with a history of colorectal adenocar-cinoma presented to the Emergency Depart-ment due to chest pain and mildly elevated cardiac serum troponin levels. Three days earlier, she had received a first adjuvant che-motherapy treatment with oral capecitabine. After the exclusion of obstructive coronary artery disease (CAD), acute myopericarditis was suspected. Conclusion: Capecitabine-induced myopericarditis is an extremely rare but important clinical condition to be recog-nized and treated promptly in order to pre -vent potentially lethal consequences of car-diac dysfunction.
展开▼
