Ursolic acid effect on atherosclerosis: Apples and apples, or apples and oranges?

摘要

Ursolic acid is a phytonutrient found in several different plant species, and of potential interest to cardiovascular research due its anti-oxidative, anti-inflammatory and other potentially cardiopro-tective properties. Although there is a wealth of data evaluating ursolic acid's biological effects, the literature is conflicted with some studies showing potentially beneficial effects while others show potentially negative effects. Furthermore, there is a paucity of research specifically investigating the potential effects of ursolic acid on atherosclerosis or vascular diseases.