Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection A Randomized Trial

Zeuzem Stefan; Ghalib Reem; Reddy K. Rajender; Pockros Paul J.; Ben Ari Ziv; Zhao Yue; Brown Deborah D.; Wan Shuyan; DiNubile Mark J.; Bach-Yen Nguyen; Robertson Michael N.; Wahl Janice; Barr Eliav; Butterton Joan R.

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Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection A Randomized Trial

机译：Grazoprevir-Elbasvir联合疗法用于初治肝硬化和非肝硬化患者的慢性丙型肝炎病毒基因型1、4或6感染的随机试验

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Background: Novel interferon- and ribavirin-free regimens are needed to treat hepatitis C virus (HCV) infection.

机译：背景：治疗丙型肝炎病毒（HCV）感染需要无干扰素和利巴韦林的新型治疗方案。

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《Annals of Internal Medicine》 |2015年第1期|共13页
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Zeuzem Stefan; Ghalib Reem; Reddy K. Rajender; Pockros Paul J.; Ben Ari Ziv; Zhao Yue; Brown Deborah D.; Wan Shuyan; DiNubile Mark J.; Bach-Yen Nguyen; Robertson Michael N.; Wahl Janice; Barr Eliav; Butterton Joan R.;
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1. Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection A Randomized Trial [J] . Zeuzem Stefan, Ghalib Reem, Reddy K. Rajender, Annals of Internal Medicine . 2015,第1期

机译：Grazoprevir-Elbasvir联合疗法用于初治肝硬化和非肝硬化患者的慢性丙型肝炎病毒基因型1、4或6感染的随机试验
2. Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV a randomized trial [J] . SulkowskiM.S., ShermanK.E., DieterichD.T., Annals of Internal Medicine . 2013,第2期

机译：替拉普韦联合治疗慢性丙型肝炎病毒基因型1感染艾滋病毒患者的一项随机试验
3. Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV a randomized trial [J] . SulkowskiM.S., ShermanK.E., DieterichD.T., Annals of Internal Medicine . 2013,第2期

机译：联合治疗与Teladrevir用于慢性丙型肝炎病毒基因型1感染患者艾滋病毒随机试验
4. DIFFERENTIAL HUMORAL RESPONSE OF GENOTYPE IB HEPATITIS C VIRUS F PROTEIN BETWEEN CHRONIC AND RECOVERED INFECTIONS [C] . Deng Xiaozhao, Kong Jing, Chu Chunli, Progress on post-genome technologies and modern natural products . 2011

机译：慢性感染和康复感染之间基因型IB型肝炎C病毒F蛋白的差异性尿液反应
5. Population pharmacokinetics and efficacy of ribavirin in patients with chronic hepatitis C genotype 1 infection. [D] . Jin, Runyan. 2010

机译：利巴韦林在慢性丙型肝炎基因型1感染患者中的群体药代动力学和功效。
6. A Cost-Effectiveness Analysis of Shortened Direct-Acting Antiviral Treatment in Genotype 1 Noncirrhotic Treatment-Naive Patients With Chronic Hepatitis C Virus [O] . Christopher G. Fawsitt, Peter Vickerman, Graham Cooke, -1

机译：基因型非肝硬化初治慢性丙型肝炎患者缩短直接作用抗病毒治疗的成本-效果分析
7. Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial [O] . JacobsonIR, Dore GJ, FosterGR, 2014

机译：Simeprevir与聚乙二醇干扰素α2a联合利巴韦林在未接受治疗的慢性丙型肝炎病毒基因型1型感染（QUEST-1）的患者中：3期，随机，双盲，安慰剂对照试验

Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection A Randomized Trial

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