MRI-based vertebral bone quality score for predicting cage subsidence by assessing bone mineral density following transforaminal lumbar interbody fusion: a retrospective analysis

摘要

Abstract Purpose This is the first study to evaluate the predictive value of the vertebral bone quality (VBQ) score on cage subsidence after transforaminal lumbar interbody fusion (TLIF) in a Chinese population using the spinal quantitative computed tomography (QCT) as the clinical standard. Meanwhile, the accuracy of the MRI-based VBQ score in bone mineral density (BMD) measurement was verified.Methods We performed a retrospective study of patients who underwent single-level TLIF from 2015 to 2020 with at least 1 year of follow-up. Cage subsidence was measured using postoperative radiographic images based on cage protrusion through the endplates more than 2?mm. The VBQ score was measured on T1-weighted MRI. The results were subjected to statistical analysis.Results A total of 283 patients (61.1% of female) were included in the study. The subsidence rate was with 14.1% (n?=?40), and the average cage subsidence was 2.3?mm. There was a significant difference in age, sex, VBQ score and spinal QCT between the subsidence group and the no-subsidence group. The multivariable analysis demonstrated that only an increased VBQ score (OR?=?2.690, 95% CI 1.312–5.515, p?=?0.007) and decreased L1/2 QCT-vBMD (OR?=?0.955, 95% CI 0.933–0.977, p?