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Therapies for Type 1 Diabetes: Is a Cure Possible?

机译:1型糖尿病的疗法:可以治愈吗?

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The current standard method for type 1 diabetes (T1D) management majorly focuses on controlling blood glucose levels with exogeneous insulin administration. Recent developments have focused on finding ways to predict and prevent the development of T1D, as well as finding a curative therapy for T1D. Such developments include #946;-cell replacement therapy by islet transplantation, non-insulin adjunct therapy, gene and stem cell-based therapies, immunotherapy, and automated treatment with an artificial pancreas. In recent years, non-traditional alternative therapy has also become a popular treatment option for T1D. This review discusses the various therapeutic options for T1D currently under various stages of development, the challenges associated with the present strategies, and their potential to eventually change the way T1D is treated.
机译:目前 1 型糖尿病 (T1D) 管理的标准方法主要侧重于通过外源性胰岛素给药来控制血糖水平。最近的发展重点是寻找预测和预防 T1D 发展的方法,以及寻找 T1D 的治愈疗法。这些发展包括胰岛移植的β细胞替代疗法、非胰岛素辅助疗法、基于基因和干细胞的疗法、免疫疗法以及人工胰腺的自动化治疗。近年来,非传统替代疗法也成为T1D的热门治疗选择。本综述讨论了目前处于不同开发阶段的T1D的各种治疗方案,与当前策略相关的挑战,以及它们最终改变T1D治疗方式的潜力。

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