A Facile and in situ Preparation Technique for Solid-Phase Microextraction Fibers with MOFs Coating

摘要

In this study, a facile preparation technique for in situ growth of MOFs-based-coated solid-phase microextraction (SPME) fibers is proposed. NH2-MIL-53 can be grown on the Al wire simply by immersing the Al wire in the solution of growth seeds and metal-organic frameworks (MOFs) successively, thereby obtaining the SPME fiber. The as-prepared fiber was combined with gas chromatography flame ionization detection (GC-FID) for the determination of non-steroidal anti-inflammatory drugs (NSAIDs) in water samples. Compared with NH2-MIL-53-coated fiber prepared with the gluing method, MIL-53-coated fiber prepared by in situ self-growth and commercial polyacrylate (PA) fiber, the as-prepared fiber demonstrated the better extraction performance, owing to more exposed adsorption sites and stronger interactions with the target. Moreover, the fiber exhibited a long service life due to multifaceted stability. After optimization of extraction and desorption conditions, the analytical method had a low-detection limit (0.002-0.05 mu gL-1), a wide linear range (0.01-500 mu gL-1) and good reproducibility (relative standard deviation < 5.84%) and provided good results for actual water samples. MOFs-based SPME fibers grown on metal wires using a facile in situ technique can maximize the extraction advantage of MOFs coating, which well promotes the application and development of MOFs in solid-phase microextraction technology.