Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

McEwen Abbye E.; Cohen Seth; Bryson-Cahn ChloeLiu CatherinePergam Steven A.Lynch JohnSchippers AdrienneStrand KathyWhimbey EstellaMani Nandita S.Zelikoff Allison J.Makarewicz Vanessa A.Brown Elizabeth R.Bakhash Shah A. MohamedBaker Noah R.Castor JaredLivingston Robert J.Huang Meei-LiJerome Keith R.Greninger Alexander L.Roychoudhury Pavitra

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Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

机译：Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

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Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1-23.3). When compared with 5174 contemporaneous samples sequenced in our laboratory, VOCs were significantly enriched among breakthrough infections (P < .05).

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《Clinical infectious diseases》 |2022年第6期|1089-1092|共4页
作者
McEwen Abbye E.; Cohen Seth; Bryson-Cahn ChloeLiu CatherinePergam Steven A.Lynch JohnSchippers AdrienneStrand KathyWhimbey EstellaMani Nandita S.Zelikoff Allison J.Makarewicz Vanessa A.Brown Elizabeth R.Bakhash Shah A. MohamedBaker Noah R.Castor JaredLivingston Robert J.Huang Meei-LiJerome Keith R.Greninger Alexander L.Roychoudhury Pavitra;
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作者单位

Dept Lab Med & Pathol,Univ Washington;

Dept Med,Univ Washington;

Vaccino & Infect Dis Div,Fred Hutchinson Canc Res CtrMed Ctr,Univ WashingtonHarborview Med Ctr,Univ Washington;

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原文格式 PDF
正文语种英语
中图分类传染病;
关键词
SARS-CoV-2; vaccine breakthrough; variants of concern; sequencing;

Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

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