Rhodamine-Based Fluorescence 'Turn-On' Chemosensor: Detection of Fe(3+)Ion in Aqueous Medium and MCF-7 Live Cells

摘要

Rhodamine-based reversible fluorescence turn-on chemosensor appended with 'N' and 'O' donor atoms as chelating moieties has been synthesized for the selective detection of Fe3+ ion over other competitive metal ions in aqueous medium. Designed probe indicated color change to pink with lower limit of detection at 1.93x10(-7) M exhibiting high sensitivity toward Fe3+ ion. Sensing mechanism was established by HRMS and NMR titration studies. The probe was successfully applied for the detection of Fe3+ ions in live MCF-7 cells.