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Cyclosporin a therapy in paraprotein‐associated neuropathy

机译:环孢菌素:一种治疗副蛋白相关神经病变的疗法

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AbstractA case of IgG paraprotein‐associated demyelinating neuropathy complicated by respiratory failure, which was unresponsive to standard immunosuppressive drug therapy, is reported. Cyclosporin A therapy resulted in a marked clinical recovery with objective improvement in nerve conduction and vital capacity. The beneficial response suggests that cell‐mediated immunity is an important pathogenetic mechanism, and that cyclosporin A may be useful in the treatment of other refractory cases of paraprotein‐associated neuro
机译:摘要报道了一例IgG副蛋白相关脱髓鞘性神经病变并发呼吸衰竭,对标准免疫抑制药物治疗无反应。环孢菌素A治疗可显著改善临床症状,并显著改善神经传导和肺活量。有益的反应表明细胞介导的免疫是一种重要的致病机制,环孢菌素 A 可能有助于治疗其他难治性副蛋白相关神经病例

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