Purpose: To estimate prevalence of prescription opioid use during pregnancy in eight US health-plans during 2001-2014.Methods! We conducted a cohort study of singleton live birth deliveries. Maternal "characteristics were ascertained from health plan and/or birth certificate data and opioids dispensed during'pregnancy from health plan pharrriacy records. Prevalence of prescription opioid use during pregnancy was calculated for any use, cumulative days pf use, and number of dispensings.
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