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Guillain–Barré syndrome in children: Clinical course, electrodiagnosis, and prognosis

机译:儿童吉兰-巴利综合征的临床病程、电诊断和预后

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AbstractThe electrodiagnostic features of acute childhood Guillain‐Barré syndrome (GBS) have not been distinguished from those in the adult. We report nerve conduction and electromyographic data from 23 children. Sixty‐one percent (14 of 23) fulfilled strict electrodiagnostic criteria for a demyelinating neuropathy, and the remainder demonstrated demyelination in at least one nerve. Reduced compound muscle action potential (CMAP) amplitude was the most common finding overall. Children10 years old. Electrodiagnostic criteria associated with poor outcome (low mean CMAP and fibrillation potentials) in previous studies, primarily of adult patients, occurred in 39 (9 of 23 children). All patients on whom follow‐up data were obtained recovered without residual disability. We conclude that electrodiagnostic prognostic indicators identified in general series of GBS may not apply to ch
机译:摘要儿童期急性吉兰-巴雷综合征(GBS)的电诊断特征与成人没有区别。我们报告了 23 名儿童的神经传导和肌电图数据。61%(23例中的14例)符合脱髓鞘性神经病变的严格电诊断标准,其余患者至少在一条神经中表现出脱髓鞘。复合肌肉动作电位 (CMAP) 振幅降低是最常见的发现。10 岁儿童。在既往研究中,与不良结局(低平均CMAP和纤维颤动电位)相关的电诊断标准主要针对成年患者,发生率为39%(23名儿童中有9名)。所有获得随访数据的患者均康复,无残余残疾。我们得出的结论是,在一般GBS系列中确定的电诊断预后指标可能不适用于ch

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