Visible-Light-Mediated Radical Aryldifluoroacetylation of N-Arylacrylamides to give Difluoroacetylated Oxindoles

摘要

A simple and practical approach to oxindole derivatives via visible-light-photocatalyzed aryldifluoroacetylation of N-arylacrylamides with BrCF2CO2Et has been developed. This method provides convenient access to a variety of difluoroester-substituted oxindoles under mild conditions.