Three Compounds Constructed from 2-Chloro-4-ferrocenylbenzoate and N-Containing Ligands: Synthesis, Crystal Structures, and Microbiological Studies

摘要

Self assemblies of the flexible ferrocenyl 2-chloro-4-ferrocenylbenzoate with Cd2+ cations in the presence of N-containing ligands result in three compounds, namely, Cd(eta(1)-OOCClH(3)C(6)Fc)(eta(2) -OOC-ClH(3)C(6)Fc)(Phen)(H2O) (I), Cd(eta(2)-OOCClH(3)C(6)Fc)(2)(2,2'-bipy) (II) and (HOOCClH(3)C(6)Fc)(2)(4,4'-bipy) (III) (Fc = (eta(5)-C5H4)Fe(eta(5)-C5H5), phen = 1,10-phenanthroline, 2,2'-bipy = 2,2'-bipyridine, 4,4'-bipy = 4,4'-bipyridine). Their structures have been determined by single-crystal X-ray diffraction analyses (CIF files CCDC nos. 1874492 (I), 1874493 (II), 1874494 (III)) and further characterized by elemental analyses, IR spectra. Crystallographic characterization shows that both I and II are mononuclear complexes exhibiting the 0D structures, while compound III gives a supramolecular structure. Notably, various C-H center dot center dot center dot Cl interactions and C-H center dot center dot center dot pi interactions are discovered in I-III, and they have significant contributions to self-assembly, which extend mononuclear structures to infinite 3D supramolecular networks. Moreover, the microbiological properties of I-III were studied. Compared with clinical drugs, I showed pretty good anti- bacterial activity. We presumed that the good lipophilic nature of I and the strong toxicity of Cd2+ ion may be responsible for the good antibacterial activities.