Use of the Multi-Coil Countercurreimt Chromatograph

摘要

The multi-coil countercurrent chromatograph which is an Ito coil planet centrifuge equipped with 8 multi-layer coils in series is useful for preparative chromatography. A table top unit was tested with three solvent systems suitable for peptide separation. Preparative separations of 2 cholecystokinin peptides were performed in the instrument resulting in their complete purification in one step.