Preparative Isolation of Pyrrolizidine Alkaloids Derived fromSenecio Vulgaris

摘要

A large scale method for the isolation of pyrrolizidine alkaloids has been adapted from a previously published analytical method. This method is a reverse phase high pressure liquid chromatography technique, utilizing a .005 M KH2PO4(pH 6.3) — methanol solvent system. The pyrrolizidine alkaloids derived fromSenecio vulgaris(common groundsel) have been utilized in this system.