Discharge anaemia is common following acute coronary syndromes (ACS). However, it is unknown if chronic anaemia (CA) and hospital-acquired anaemia (HAA) are associated with similar outcomes. In this retrospective analysis of 4083 ACS admissions treated with percutaneous coronary intervention in Switzerland (SPUM-ACS registry), 1896 patients (46.4) had discharge anaemia (CA: n = 643 (15.7) vs. HAA: n = 1253 (30.7)). Landmark analysis that matched patients with CA (n = 504) and HAA (n = 866) with non-anaemic patients found increased 1 -year major adverse cardiovascular events (cardiovascular mortality, myocardial infarction, stroke) among patients with CA (6.9 vs. 3.0, HR 2.073, 95 CI 1.039-4.134, p = 0.039) and HAA (3.8 vs. 2.3, HR 1.772, 95 CI 1.002-3.232, p = 0.049). Only CA was associated with increased 1 -year all-cause mortality (7.9 vs. 1.6, HR 4.255, 95 CI 1.950-9.284,p< 0.001). CA and HAA were associated with poor 1-year cardiovascular outcomes. Only CA was associated with increased all-cause mortality suggesting that HAA and CA represent distinct subclinical entities.
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机译：出院性贫血在急性冠脉综合征 （ACS） 后很常见。然而，尚不清楚慢性贫血 （CA） 和医院获得性贫血 （HAA） 是否与相似结局相关。在这项对瑞士接受经皮冠状动脉介入治疗的 4083 例 ACS 入院患者的回顾性分析（SPUM-ACS 登记处）中，1896 例患者 （46.4%） 出现出院性贫血（CA：n = 643 （15.7%） vs. HAA：n = 1253 （30.7%））。将 CA （n = 504） 和 HAA （n = 866） 患者与非贫血患者进行匹配的标志性分析发现，CA （6.9% vs. 3.0%，HR 2.073,95% CI 1.039-4.134，p = 0.039）和 HAA（3.8% vs. 2.3%，HR 1.772,95% CI 1.002-3.232，p = 0.049）患者的 1 年主要不良心血管事件（心血管死亡率、心肌梗死、卒中）增加。只有CA与1年全因死亡率增加相关（7.9% vs. 1.6%，HR 4.255,95%CI 1.950-9.284，p< 0.001）。CA 和 HAA 与不良的 1 年心血管结局相关。只有 CA 与全因死亡率增加相关，表明 HAA 和 CA 代表不同的亚临床实体。
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