Non-adherence to ivabradine and placebo and outcomes in chronic heart failure: an analysis from SHIFT

摘要

AimsIn heart failure, non-adherence increases events; in turn, the effect of hospitalization on adherence is incompletely understood. We explored the relationship of non-adherence to outcomes, hospitalizations with non-adherence, and the influence of non-adherence on treatment effects of heart rate lowering with ivabradine.