Synthesis and Biological Activity of Divalent Metal Chelates of Metronidazole

摘要

The complexing behaviour of metronidazoel (1H-imidazole-1-ethanol-2-methyl-5-nitro)towards Co(II), Ni(II), and Cu(II) has been studied. The complexes of the general formula ML_2X_2.2H_2O adn CuL_4Cl_2 [where M = Co(II) or Ni(II)], L = C_6H_9N_3O_3 (drug) as ligand) and X = Cl~-] have been prepared and characterised by elemental analysis, molar conductance, magnetic suspceptibility measurements, electronic and infrared spectral data. They have also been tested for their antibacterial activities.