Antimicrobial and Antimycobacterial Activity of Some Quinoxalines 'N' Bridgehead Heterocycles

摘要

Quinoxalin-2,3-diones (1) on treatment with o-phenylenedi-amine afforded 6,11 -dihydro-5,6,-11,12-tetraazanaphthacene (3).2,3-Dichloroquinoxaline (2) on condensation with anthra-nilic acid,o-phenylenediamine and sodium azide yielded bis[quinazolino(3,2a)quinoxaline]-11,18-diones (4),bis[benz-imidazolo(1,2a)quinoxaline] (5) and bis-[1,2,3,4-tetrazoIo (1,5a)quinoxaline] (6),respectively.The structures have been established by IR,mass spectral and elemental analysis.These compounds have been evaluated for their antibacterial,antifungal and antitubercular activity.