One-Pot Synthesis of Dialkyl 2-[(2,5-Dioxo-1-pyrrolidinyl)-oxy]-2-butenedioates from Acetylenic Esters and n-Hydroxysuccinimide

摘要

A one-pot synthesis of electron-poor O-vinyl pyrrolidine in fairly high yields by the reaction of N-hydroxysuccinimide and dialkyl acetylenedicarboxylates in water-acetone media is reported.The structures of these compounds were confirmed by IR,~1H and ~(13)C NMR spectroscopy.The NMR spectra indicated that E-and Z-isomers of the products are formed.