The chemistry of imines has been a topic of interest over the past 30 years due to their importance in organic synthesis.Many N-substituted imines have been prepared and applied to the preparation of amino acids,beta-lactams,heterocycles,alkaloids,aziridines,and amines.They are especially useful for the synthesis of optically active alpha-amino acids which are one of the most important types of chiral molecules for the preparation of natural products and complex biologically active compounds and the construction of selective drugs.
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