Esophageal Prostaglandins in Guinea Pigs and Rats

摘要

The synthesis of prostaglandins (PGs) in the mucosa of the esophagus is studied in 20 albinotic adult guinea pigs and rats using the radioimmunoassay method. Both species investigated synthesize five PGs. The PG synthesis activity in the guinea pig’s esophagus is higher than that in the rat’s. PGE2 and PGF2α might be involved in the regulation of lower esophagus sphincter pres