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Synthesis of Biologically Active and Novel Antifungal Agents Like Substituted Hetero Aryl amines of Dihydro Imidazo[1,2-a]pyridine Derivatives

机译:二氢咪唑并[1,2-a]吡啶衍生物的取代的杂芳基胺等生物活性和新型抗真菌剂的合成

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摘要

Some substituted hetero aryl amines of dihydro imidazo[1,2-a]pyridine-3yl-methyl derivatives were synthesized and the final compounds elucidated by FTIR, ~1H NMR, MASS and micro analysis and were evaluated for antifungal activity by Candida albcans. The preliminary results showed that all of the tested compounds were protective against Candida albcans at 50-200 mcg/mL concentrations levels.
机译:合成了二氢咪唑并[1,2-a]吡啶-3基-甲基衍生物的一些取代的杂芳基胺,并通过FTIR,〜1H NMR,MASS和显微分析阐明了最终化合物,并通过白色念珠菌评估了其抗真菌活性。初步结果表明,所有测试的化合物在浓度为50-200 mcg / mL时均对白念珠菌具有保护作用。

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