In‐line filtration of platelet concentrates obtained with the OmnixTMblood cell separator

摘要

SUMMARY.The quality of platelet concentrates (PC) obtained with the blood cell separator OmnixTMwas investigated before and after in‐line filtration. PC were filtered 2h (protocol A) and 4h (protocol B) after the termination of apheresis. Platelet (PLT) yield after filtration was similar in both protocols (median 3.7 vs. 3.4 times 1011). Median white blood cell (WBC) contamination after leucocyte depletion was 0.07 times 106(range 0.02–3.27 times 106) in protocol A and 0.06 times 106(range 0.02–2.1 times 106) in protocol B. Glucose, lactate, lactate dehydrogenase, morphology score and pH value were not statistically different before and after filtration in both protocols. We conclude that in‐line filtration results in sufficient leucocyte depletion of the PC. The prefiltration storage time did not influence the studied parameters of product