A Facile Synthesis of 3-Substituted-2-styryl-4-quinazolones

摘要

2-Methyl-3,1-benzoxazine-4-one(3),generated by cyclizing of N-acetyl-anthranilic acid with ethyl chloroformate in benzene containing triethyl-amine,reacts with primary amine and subsequently aromatic aldehyde when heated under reflux in glacial acetic acid to give 3-substi-tuted 2-styryl-3,4-dihydro-4-quinazolones(7).