Copper(I)-Catalyzed N-Arylation of N~1,N3-Dibenzylmalonamide and N~1,N~3-Dibutylmalonamide Followed by Cleavage of the Malonyl Group with Aryl Halides Under Ligand-Free Conditions

摘要

We primarily developed a practical and convenient protocol to synthesize of aromatic amines based on Cul-catalyzed N-arylation of N~1 ,N~3-dibenzylmalonamide and N~1 ,N~3-dibutylmalonamide followed by cleavage of the malonyl group with aryl halides under ligand-free conditions giving good yields.