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Qualitative Analysis of Anti-protozoan Drug Tinidazole by Vibrational and UV-Visible Spectroscopy

机译:抗原生动物药物替硝唑的振动和紫外-可见光谱定性分析

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摘要

Modern spectroscopic techniques serve as indispensable tools for the qualitative analysis of pharmaceutical products. In this work,a qualitative analysis of a commonly used anti-protozoan drug,tinidazole has been carried out using FTIR,FT-Raman and UV-visible spectroscopic techniques. A satisfactory vibrational band assignment of the drug has been made based on the position,shape and relative intensity of the recorded spectra,in correlation with bands assigned in structurally related molecules. The quality of the drug has been studied by storing it in different conditions and analyzing their spectra by internal standard ratio method. The stress degradation behaviour of the drug has been studied by employing FTIR and UV-Visible spectral techniques.
机译:现代光谱技术是药物产品定性分析不可或缺的工具。在这项工作中,已使用FTIR,FT-Raman和UV-可见光谱技术对常用的抗原生动物药物替硝唑进行了定性分析。根据记录光谱的位置,形状和相对强度,与在结构相关分子中分配的谱带相关,对药物进行了令人满意的振动谱带分配。通过在不同条件下储存药物并通过内标比方法分析其光谱,研究了药物的质量。已通过采用FTIR和UV-可见光谱技术研究了药物的应力降解行为。

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