Peptidylarginine Deiminase From Porphyromonas gingivalis Citrullinates Human Fibrinogen and alpha-Enolase Implications for Autoimmunity in Rheumatoid Arthritis

Wegner Natalia; Wait Robin; Sroka Aneta; Eick Sigrun; Nguyen Ky-Anh; Lundberg Karin; Kinloch Andrew; Culshaw Shauna; Potempa Jan; Venables Patrick J.

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Peptidylarginine Deiminase From Porphyromonas gingivalis Citrullinates Human Fibrinogen and alpha-Enolase Implications for Autoimmunity in Rheumatoid Arthritis

机译：牙龈卟啉单胞菌的肽基精氨酸去亚氨酶瓜氨酸化人纤维蛋白原和α-烯醇化酶在类风湿关节炎中的自身免疫意义

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Objective. To investigate protein citrullination by the periodontal pathogen Porphyromonas gingivalis as a potential mechanism for breaking tolerance to citrullinated proteins in rheumatoid arthritis (RA).

机译：目的。研究牙周病原体牙龈卟啉单胞菌（Porphyromonas gingivalis）的蛋白质瓜氨酸化，作为打破类风湿性关节炎（RA）对瓜氨酸化蛋白的耐受性的潜在机制。

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《Arthritis and Rheumatism》 |2010年第9期|共11页
作者
Wegner Natalia; Wait Robin; Sroka Aneta; Eick Sigrun; Nguyen Ky-Anh; Lundberg Karin; Kinloch Andrew; Culshaw Shauna; Potempa Jan; Venables Patrick J.;
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正文语种 eng
中图分类免疫性疾病;
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1. Peptidylarginine Deiminase From Porphyromonas gingivalis Citrullinates Human Fibrinogen and alpha-Enolase Implications for Autoimmunity in Rheumatoid Arthritis [J] . Wegner Natalia, Wait Robin, Sroka Aneta, Arthritis and Rheumatism . 2010,第9期

机译：牙龈卟啉单胞菌的肽基精氨酸去亚氨酶瓜氨酸化人纤维蛋白原和α-烯醇化酶在类风湿关节炎中的自身免疫意义
2. Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis [J] . Montgomery Anna B., Kopec Jolanta, Shrestha Leela, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2016,第6期

机译：牙龈卟啉单胞菌肽酰精氨酸脱亚氨酶的晶体结构：对类风湿关节炎自身免疫的影响
3. Expression of anti-Porphyromonas gingivalis peptidylarginine deiminase immunoglobulin G and peptidylarginine deiminase-4 in patients with rheumatoid arthritis and periodontitis [J] . Journal of periodontal research . 2016,第1期

机译：类风湿关节炎和牙周炎患者抗牙龈卟啉单胞菌肽丝氨酸精氨酸脱亚氨酶免疫球蛋白G和肽基丝氨酸精氨酸脱亚氨酶-4的表达
4. Determination of Citrullinated Sites of Alpha-fibrinogen in Rheumatoid Arthritis Synovial Fluid Using Immunocapture and Two Dimensional Liquid Chromatography Mass Spectrometry [C] . Khue Truong, Yunan Miao, Roger Moore, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：用免疫抑制和二维液相色谱法质谱法测定类风湿性关节炎滑液中α-纤维蛋白原的酸化位点
5. Kinetic characterization of protein arginine deiminase 4: An enzyme dysregulated in rheumatoid arthritis. [D] . Bhatia, Monica. 2007

机译：精氨酸脱亚氨酶4的动力学表征：类风湿关节炎中失调的一种酶。
6. Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis [O] . Natalia Wegner, Robin Wait, Aneta Sroka, -1

机译：来自卟啉核糖蛋白的肽氨基氨酰亚胺酸瓜瓜酸盐人纤维蛋白原和α-烯醇酶：对类风湿性关节炎的自身免疫影响
7. Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. [O] . Wegner, N, Wait, R, Sroka, A, 2010

机译：牙龈卟啉单胞菌（Porphyromonas gingivalis citrullin）的肽酰精氨酸去亚氨酶可修饰人纤维蛋白原和α-烯醇化酶：对类风湿关节炎自身免疫的影响。

Peptidylarginine Deiminase From Porphyromonas gingivalis Citrullinates Human Fibrinogen and alpha-Enolase Implications for Autoimmunity in Rheumatoid Arthritis

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