Localization of the human GM-CSF receptor β chain gene (CSF2RB) to chromosome 22q12.2→q13.1

摘要

The gene for the β-chain of the human GM-CSF receptor (CSF2RB) has been mapped to chromosome 22 by PCR analysis of a series of human × rodent somatic cell hybrids. In situ hybridization to normal human chromosomes and two translocations involving chromosome 22 and the chromosome expessing the rare fragile site FRA22A place the gene in the region 22q12.2→q13.1, proximal to the fragile s