Synthesis and Evaluation of Mannich Bases of 2-(Benzimida- zolylaminomethyl)thiazolidin-4-one as Antimicrobial Agents

Pankaj Srivastava; Munendra M. Varshney; Dheeraj Kumar

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Synthesis and Evaluation of Mannich Bases of 2-(Benzimida- zolylaminomethyl)thiazolidin-4-one as Antimicrobial Agents

机译：2-（苯甲酰亚胺基-唑基氨甲基）噻唑烷酮-4-酮曼尼希碱的合成及评价

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Mannich bases of 2-(benzimidazolylaminomethyl) thiazolidin-4-one are synthesized by amination at position 5 using formaldehyde and various secondary amines. The prepared compounds have been characterized by physico-chemical and spectral analysis and screened for their antibacterial activity.

机译：2-（苯并咪唑基氨甲基）噻唑烷-4-酮的曼尼希碱是通过甲醛和各种仲胺在5位胺化而合成的。制备的化合物已通过理化和光谱分析进行了表征，并对其抗菌活性进行了筛选。

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《Asian Journal of Chemistry: An International Quarterly Research Journal of Chemistry》 |2009年第6期|共5页
作者
Pankaj Srivastava; Munendra M. Varshney; Dheeraj Kumar;
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正文语种 eng
中图分类化学工业;
关键词
Benzimidazole; Mannich base; Condensation reaction .;

机译：苯并咪唑;曼尼希碱;缩合反应;

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1. Synthesis and Evaluation of Mannich Bases of 2-(Benzimida- zolylaminomethyl)thiazolidin-4-one as Antimicrobial Agents [J] . Pankaj Srivastava, Munendra M. Varshney, Dheeraj Kumar Asian Journal of Chemistry: An International Quarterly Research Journal of Chemistry . 2009,第6期

机译：2-（苯甲酰亚胺基-唑基氨甲基）噻唑烷酮-4-酮曼尼希碱的合成及评价
2. One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents [J] . PansareD.N., MullaN.A., PawarC.D., Bioorganic and Medicinal Chemistry Letters . 2014,第15期

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3. Synthesis and Biological Evaluation of Some Novel Mannich Bases of Isoxazoline Derivatives as Possible Antimicrobial Agents [J] . Seema A. Gosavi, Dattatray H. Nandal, Sarita S. Pawar Asian Journal of Chemistry: An International Quarterly Research Journal of Chemistry . 2019,第12期

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4. Combinatorial synthesis of mannich bases in solution/polymer reagent workup [C] . Wenqiang HUANG, Shaoling Cheng, Yu CHEN, Pacific polymer conference preprints . 1999

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5. Stereoselective Synthesis and Biological Evaluation of Pyrrolidine Natural Products and 4-Oxazolidinone Antimicrobial Agents [D] . Edwards, Grant Alan. 2020

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6. 5-Benzyliden-2-(5-methylthiazol-2-ylimino)thiazolidin-4-ones as Antimicrobial Agents. Design Synthesis Biological Evaluation and Molecular Docking Studies [O] . Michelyne Haroun, Christophe Tratrat, Aggeliki Kolokotroni, 2021

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Synthesis and Evaluation of Mannich Bases of 2-(Benzimida- zolylaminomethyl)thiazolidin-4-one as Antimicrobial Agents

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