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Stem cell-mediated neovascularization in heart repair.

机译:干细胞介导的心脏修复中的新生血管形成。

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摘要

Accumulating clinical and experimental evidence indicates that stem cells from various sources are promising in the treatment of cardiac dysfunction. They may be incorporated into neovascular foci and thus contribute to postnatal physiological and pathological vasculogenesis and/or produce a variety of growth factors for angiogenesis and cytokines that home other stem cells from other organs for cardiac regeneration. This review focuses on the neovascularization of stem cells from different sources in cardiac repair, with emphasis on adult stem cells.
机译:不断积累的临床和实验证据表明,来自各种来源的干细胞在治疗心功能不全方面具有前景。它们可能被整合到新生血管病灶中,从而有助于出生后的生理和病理性血管生成和/或产生多种用于血管生成的生长因子和细胞因子,这些细胞因子将来自其他器官的其他干细胞用于心脏再生。本文重点介绍不同来源干细胞在心脏修复中的新生血管形成,重点是成体干细胞。

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