Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukaemia Survivors Enrolled Between 1971 and 1998 in EORTC CLG Studies: Results of the 58 Late Adverse Effects Study

摘要

(Abstracted from Hum Reprod 2022;37:44–53) Childhood acute lymphoblastic leukemia (ALL) has an expected cure rate of greater than 90%, reflecting a vast improvement in diagnosis and treatment over the last 40 years. Fertility impairment is among the chief concerns of long-term survivors because of possible damage to reproductive organs or hormonal balance stemming from treatment.