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首页> 外文期刊>Archives of Oral Biology >Genetic variants in microRNA-146a (C > G) and microRNA-1269b (G > C) are associated with the decreased risk of oral premalignant lesions, oral cancer, and pharyngeal cancer
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Genetic variants in microRNA-146a (C > G) and microRNA-1269b (G > C) are associated with the decreased risk of oral premalignant lesions, oral cancer, and pharyngeal cancer

机译:microRNA-146a(C> G)和microRNA-1269b(G> C)中的遗传变异与口腔癌前病变,口腔癌和咽癌的风险降低相关

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摘要

Objective: To investigate the relationships between two single-nucleotide polymorphisms at miR-146a C > G (rs2910164) and miR-1269b G > C (rs7210937) and the risk of developing oral premalignant lesions (OPLs), oral squamous cell carcinoma (OSCC), pharyngeal SCC (PSCC), and oral and pharyngeal SCC (OPSCC).
机译:目的:探讨miR-146a C> G(rs2910164)和miR-1269b G> C(rs7210937)的两个单核苷酸多态性与发生口腔癌前病变(OPL),口腔鳞状细胞癌(OSCC)的风险之间的关系。 ),咽SCC(PSCC)以及口腔和咽SCC(OPSCC)。

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